Does Digestive Enzymes Help With Co-ingestion of a microbial protease mixture with whey pr...?

Evidence Summary

Co-ingestion of a microbial protease mixture with whey protein modestly enhanced early postprandial essential amino acid and branched-chain amino acid availability by ~14-15% and reduced ghrelin while increasing satiety signals in healthy adults (PMID: 40675336). A multi-functional GI primer supplement containing digestive enzymes among other ingredients improved self-reported digestive symptoms, stool consistency, and quality-of-life measures over 14 days in participants with mild digestive complaints (PMID: 39339773). However, the evidence base from the provided papers is limited and does not isolate digestive enzymes as standalone interventions in rigorous, large-scale human trials.

Source: auto-research

Effective Dose

No established dose from provided studies for human supplementation