Last verified: 17 days ago
Glutathione
Also known as: GSH, L-glutathione, reduced glutathione, gamma-glutamylcysteinylglycine
Evidence under review. — Not yet rated
Body's master antioxidant. Supplement evidence is limited; most data comes from measuring it as a biomarker.
-
What it does
Glutathione is the body's most abundant internal antioxidant, a tripeptide molecule produced naturally in every cell. In the provided research, glutathione (and related enzymes like glutathione...
-
Evidence quality
Evidence base hasn't been formally rated yet. See research below.
-
Clinical dose
No established dose
What the Science Says
Glutathione is the body's most abundant internal antioxidant, a tripeptide molecule produced naturally in every cell. In the provided research, glutathione (and related enzymes like glutathione peroxidase) appears repeatedly as a biomarker of oxidative stress — rising when the body is under stress and falling when antioxidant defenses are overwhelmed. None of the provided studies tested oral glutathione supplementation directly, so no dose or timeframe for human benefit can be established from this data.
What It Doesn't Do
No evidence from these studies that taking glutathione pills raises your blood glutathione levels. Not proven to detox your liver, brighten skin, or reverse aging. Don't confuse measuring it as a biomarker with proving a supplement works. No data here supports any specific health claim for oral glutathione.
Evidence-Based Benefits
Glutathione levels in blood reflect how much oxidative stress the body is under.
Weak EvidenceEffective at: No established dose
Supporting studies (click to view on PubMed):
Absorption & Bioavailability
Unknown — none of the provided studies tested oral glutathione absorption or bioavailability in humans.
Red Flags to Watch For
- None of the provided studies tested glutathione as a standalone oral supplement — all references are to it as a biomarker, not an intervention.
- Products making skin-whitening or liver-detox claims have no support in this evidence set.
- Glutathione is widely sold in 1,000+ registered products (NIH DSLD) despite a near-total absence of direct clinical trial evidence in the provided data.
- Marketing often conflates the body's natural glutathione activity with benefits from taking a pill — these are not the same thing.
Products Containing Glutathione
See how Glutathione is used in these analyzed products:
Garden of Life Vitamin Code Men's Multi
Halo Beauty Hair Skin Nails Booster
Supplement
Smartvita Men's Total Synergy Multivitamins
Supplement
Cheers Restore After-Alcohol Aid
Supplement
Craving Control
Supplement
Micro Ingredients Liver Advanced+
Supplement
Cymbiotika Liposomal Glutathione
Supplement
Vitabiotics Neuromind Plus
Supplement
Transparent Labs Nitric Oxide
Supplement
No Days Wasted DHM Detox
Supplement
Jarro-Dophilus® EPS - 10 Billion CFU
Supplement
Fortheageless
Supplement
Thorne Amino Complex Berry Powder NSF
Supplement
NAC 600mg (Pure Encapsulations)
Supplement
Smartvita Women's Total Synergy Multivitamins
Supplement
The Absorption Company Energy
Supplement
Hunter Focus
Supplement
Life Extension Mix Capsules
Supplement
Brain & Memory Power Boost
Supplement
NutraBio Liver
Supplement
Frequently Asked Questions
What does Glutathione do?
Body's master antioxidant. Supplement evidence is limited; most data comes from measuring it as a biomarker.
What is the effective dose of Glutathione?
No established dose
Is Glutathione safe?
None of the provided studies tested glutathione as a standalone oral supplement — all references are to it as a biomarker, not an intervention.
What doesn't Glutathione do?
No evidence from these studies that taking glutathione pills raises your blood glutathione levels.
Research Sources
- PubMed
- NIH DSLD
This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Last updated: 2026-05-25