Does Hawthorn Berry Help With In rat models, hawthorn berry extract (HBE) demonstrated ...?

Evidence Summary

In rat models, hawthorn berry extract (HBE) demonstrated antioxidant, anti-inflammatory, hypolipidemic, antiapoptotic, and antifibrotic effects against obesity-induced cardiac injury, reducing markers like IL-1β, IL-6, TNF-α, and improving lipid profiles (PMID: 39689383). In a separate rat colitis model, HBE reduced neutrophil infiltration, lipid peroxidation, and edema, suggesting anti-inflammatory and antioxidant properties attributable to compounds like oleanolic and ursolic acid (PMID: 23875899). One human clinical trial included hawthorn berry as part of a multi-ingredient nitric oxide supplement (Neo40 Daily), which significantly increased plasma nitrite/nitrate and reduced triglycerides, but hawthorn's individual contribution cannot be isolated (PMID: 21530799).

Source: auto-research

Effective Dose

No established dose (insufficient research data)