Does Hops Help With A valerian-hops combination (Ze 91019) showed a statistic...?

Evidence Summary

A valerian-hops combination (Ze 91019) showed a statistically significant increase in sleep duration of ~21.7 minutes versus placebo in a small feasibility RCT (PMID: 40462685). Xanthohumol, a flavonoid from hops, was safe and well-tolerated at 24 mg/day in Crohn's disease patients and showed potential hepatic and metabolic benefits (PMID: 41834265). Iso-alpha acids from hops reduced LTA-induced inflammatory cytokine (IL-6, IL-1β) release in human monocytes in a small crossover study, likely via JNK inhibition (PMID: 41793519).

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Effective Dose

No established dose from provided studies alone; valerian-hops combination used at unspecified dose; xanthohumol studied at 24-172 mg/day; iso-alpha acids at 15 mg