Last verified: 102 days ago
Lactobacillus reuteri ATCC PTA 6475
Also known as: L. reuteri ATCC PTA 6475, Lactobacillus reuteri 6475, L. reuteri PTA 6475
Evidence under review. — Not yet rated
Probiotic strain with early evidence for bone health and gut microbiota support in older women.
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What it does
Lactobacillus reuteri ATCC PTA 6475 is a specific strain of probiotic bacteria originally isolated from humans. In a clinical trial of older women with low bone mineral density, one year of daily...
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Evidence quality
Evidence base hasn't been formally rated yet. See research below.
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Clinical dose
No established dose from provided studies
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Found in
What the Science Says
Lactobacillus reuteri ATCC PTA 6475 is a specific strain of probiotic bacteria originally isolated from humans. In a clinical trial of older women with low bone mineral density, one year of daily supplementation helped preserve gut microbiota diversity and reduce inflammatory markers compared to poor responders. Early lab research also suggests it may influence immune cell activity and promote healthy cell turnover in the gut, though most of this work is from animal or cell studies, not human trials.
What It Doesn't Do
Not proven to treat or prevent osteoporosis on its own. No human evidence it prevents cancer. Animal and cell studies on cancer protection don't translate directly to humans. No proven benefit for anxiety or mood in people — the piglet study doesn't count. Don't expect dramatic results without a healthy diet and lifestyle.
Evidence-Based Benefits
One year of daily supplementation helped slow bone loss in older women with low bone mineral density.
Weak EvidenceEffective at: No established dose from provided studies
Supporting studies (click to view on PubMed):
Daily supplementation preserved gut microbiota gene richness and reduced inflammation in older women.
Weak EvidenceEffective at: No established dose from provided studies
Supporting studies (click to view on PubMed):
Activates specific immune cells in lab and animal models, potentially supporting immune balance.
Weak EvidenceEffective at: No established dose from provided studies
Supporting studies (click to view on PubMed):
Absorption & Bioavailability
Unknown — the provided studies do not report on colonization rates or systemic absorption of this specific strain in humans.
Red Flags to Watch For
- Most exciting findings (cancer protection, mood effects) come from animal or cell studies, not human clinical trials
- Only one small human RCT on bone health is referenced; results may not apply broadly
- Specific effective dose in CFUs is not reported in the provided studies, making it hard to evaluate product labels
- Over 1,000 supplement products on the market use this strain, but clinical evidence remains very limited
Products Containing Lactobacillus reuteri ATCC PTA 6475
See how Lactobacillus reuteri ATCC PTA 6475 is used in these analyzed products:
Frequently Asked Questions
What does Lactobacillus reuteri ATCC PTA 6475 do?
Probiotic strain with early evidence for bone health and gut microbiota support in older women.
What is the effective dose of Lactobacillus reuteri ATCC PTA 6475?
No established dose from provided studies
Is Lactobacillus reuteri ATCC PTA 6475 safe?
Most exciting findings (cancer protection, mood effects) come from animal or cell studies, not human clinical trials
What doesn't Lactobacillus reuteri ATCC PTA 6475 do?
Not proven to treat or prevent osteoporosis on its own.
Research Sources
- PubMed
- NIH DSLD
This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Last updated: 2026-05-25