Does Lutein Help With Lutein supplementation reliably raises serum and plasma l...?

Evidence Summary

Lutein supplementation reliably raises serum and plasma lutein concentrations in a dose-dependent manner and can increase macular pigment optical density (MPOD), particularly in individuals with low baseline MPOD levels (PMID: 20599660, PMID: 26451726). At 12 mg/day over 12 weeks, it improved contrast sensitivity in subjects with long-term computer screen exposure (PMID: 19586568). At 10 mg/day over 12 months, it significantly reduced circulating complement factors CFD, C5a, and C3d, suggesting systemic anti-inflammatory effects relevant to macular degeneration (PMID: 24009749), and at 20 mg/day it reduced inflammatory cytokines IL-6 and MCP-1 and lowered LDL and triglycerides in early atherosclerosis patients (PMID: 23154578).

Source: auto-research

Effective Dose

6-20 mg daily based on study doses