Mango Extract
Also known as: Mangifera indica extract, mango polyphenols, mango peel extract, mango seed kernel extract, MPE
Effective Dosage
No established dose (insufficient research data)
What the Science Says
Mango extract comes from the fruit, peel, or seed kernel of the mango tree (Mangifera indica) and is rich in polyphenols like gallic acid and gallotannins. Lab and animal studies suggest it may reduce inflammation, protect cells from oxidative stress, and support gut and joint health. However, all available evidence comes from cell cultures and animal models — no human clinical trials were found in the provided data.
What It Doesn't Do
Not proven to work in humans — every study found was in animals or test tubes. Won't reliably treat acne, arthritis, or colitis based on current evidence. No proven dose for humans. Don't expect anti-aging or liver-protecting effects just from taking a supplement capsule.
Evidence-Based Benefits
Mango extract is derived from the fruit of the mango tree and has been studied for its potential antioxidant properties. Limited research suggests it may have some health benefits, but the evidence is not robust enough to draw definitive conclusions.
Weak EvidenceEffective at: Unknown (insufficient research data)
Source: auto-research
Absorption & Bioavailability
Unknown — no human pharmacokinetic or bioavailability data in the provided studies. Topical formulations were specifically engineered (microemulsion) to improve skin delivery, suggesting raw extract may have absorption challenges.
Red Flags to Watch For
- Zero human clinical trials in the provided evidence — all findings are from animals or cell cultures and may not translate to people
- No established safe or effective dose for humans has been determined from these studies
- Products containing mango extract are often combined with other ingredients (e.g., lemongrass oil), making it impossible to attribute effects to mango alone
- Over 1,000 supplement products on the market despite extremely limited human evidence — marketing far outpaces the science
- Animal study doses (100–400 mg/kg) are very high and don't directly translate to human supplement dosing
Research Sources
- PubMed
- NIH DSLD
This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Last updated: 2026-04-06