Does Nettle Root Help With Nettle root extract has shown modest but statistically si...?

Evidence Summary

Nettle root extract has shown modest but statistically significant improvement in International Prostate Symptom Score (IPSS) for benign prostatic hyperplasia (BPS/BPH) compared to placebo in a 12-month RCT (PMID: 15045190). In combination with saw palmetto, it demonstrated equivalent efficacy to finasteride in improving urinary flow and symptom scores in BPH patients, with better tolerability than finasteride (PMID: 10971268). In vitro studies suggest antiproliferative effects on prostate epithelial cancer cells and possible anti-inflammatory mechanisms involving SHBG and aromatase modulation, though clinical relevance of these mechanisms remains unconfirmed (PMID: 17509841, PMID: 10705733).

Source: auto-research

Effective Dose

459 mg/day dry extract based on clinical trial data