Oligopeptide-2
Also known as: Acetyl Tetrapeptide-3, hair growth peptide, synthetic hair peptide
Effective Dosage
No established dose
What the Science Says
Oligopeptide-2 is a small synthetic protein fragment (peptide) primarily used in cosmetic formulations targeting hair growth and scalp health. It is marketed as a compound that may mimic growth factors involved in hair follicle stimulation, potentially encouraging hair density and reducing shedding. However, there is no published peer-reviewed clinical evidence indexed in major databases to confirm these effects in humans, and any claims about its efficacy are based on manufacturer-sponsored data or in-vitro (lab dish) testing rather than independent clinical trials.
What It Doesn't Do
Not proven to regrow hair in humans — no independent clinical trials exist. Won't replace proven hair loss treatments like minoxidil or finasteride. No evidence it works better than a placebo. Lab results don't automatically translate to real-world results on your scalp.
Evidence-Based Benefits
Oligopeptide-2 is a small synthetic protein fragment (peptide) primarily used in cosmetic formulations targeting hair growth and scalp health. It is marketed as a compound that may mimic growth factors involved in hair follicle stimulation, potentially encouraging hair density and reducing shedding. However, there is no published peer-reviewed clinical evidence indexed in major databases to confirm these effects in humans, and any claims about its efficacy are based on manufacturer-sponsored data or in-vitro (lab dish) testing rather than independent clinical trials.
Weak EvidenceEffective at: No established dose
Source: auto-research
Absorption & Bioavailability
Unknown — peptides applied topically face significant absorption barriers through the skin. Whether Oligopeptide-2 penetrates to the hair follicle level in meaningful concentrations has not been established in published research.
Red Flags to Watch For
- Zero independent peer-reviewed clinical trials published in major databases — all efficacy claims appear to originate from manufacturers
- Cosmetic peptides are frequently marketed with exaggerated 'clinical study' language that refers to small, unpublished, or industry-funded tests
- No regulatory approval (FDA or equivalent) for hair regrowth claims — products using this ingredient are sold as cosmetics, not drugs
- High price point products often use peptide ingredients as marketing tools without dose transparency or proven delivery mechanisms
- Absence from NIH supplement databases and clinical trial registries suggests very limited scientific scrutiny
Products Containing Oligopeptide-2
See how Oligopeptide-2 is used in these analyzed products:
Research Sources
- General knowledge — no published papers were available for this ingredient in the provided data
This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Last updated: 2026-04-09