Orlistat
Also known as: Alli, Xenical, tetrahydrolipstatin
Effective Dosage
60-120 mg daily
โ What the Science Says
Orlistat is a weight-loss medication that works by inhibiting the absorption of dietary fats in the intestines. Clinical trials have shown that it can lead to significant weight loss when combined with a reduced-calorie diet and exercise.
โ What It Doesn't Do
Orlistat does not promote weight loss without dietary changes; it is not a magic pill. It does not improve overall health markers like cholesterol or blood pressure on its own and is not effective for everyone.
Evidence-Based Benefits
Orlistat is a weight-loss medication that works by inhibiting the absorption of dietary fats in the intestines. Clinical trials have shown that it can lead to significant weight loss when combined with a reduced-calorie diet and exercise.
Strong EvidenceEffective at: 60-120 mg daily
Source: auto-research
Absorption & Bioavailability
Poor - Orlistat is not well absorbed systemically, as it primarily acts locally in the gastrointestinal tract.
Red Flags to Watch For
- ๐ฉ May cause gastrointestinal side effects such as oily stools and flatulence
- ๐ฉ Not suitable for individuals with certain medical conditions, such as malabsorption syndromes
Products Containing Orlistat
See how Orlistat is used in these analyzed products:
Research Sources
- PubMed
- NIH DSLD
This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Last updated: 2026-02-22