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Does Pancreatin Help With Pancreatin is a mixture of digestive enzymes — including ...?

Moderate Evidence

Evidence Summary

Pancreatin is a mixture of digestive enzymes — including lipase, protease, and amylase — derived from animal pancreatic tissue. In people whose pancreas cannot produce enough enzymes (such as after pancreatic surgery or with pancreatic cancer), pancreatin replacement therapy has been shown in clinical trials to help maintain body weight, improve protein absorption, and reduce complications like fatty liver disease. High-dose pancreatin (around 40,000 IU per meal, 3x/day) produced meaningful improvements in nutritional markers like prealbumin within 3 months in post-surgical patients.

Source: auto-research

Effective Dose

No established dose for healthy adults; clinical studies used 40,000 IU (3x/day with meals) or 3.0–12.0 g/day in post-surgical patients

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