Does Phosphatidylserine Help With Phosphatidylserine (PS) supplementation showed modest cog...?

Evidence Summary

Phosphatidylserine (PS) supplementation showed modest cognitive benefits in older adults with mild cognitive impairment (MCI) when combined with alpha-linolenic acid and Ginkgo flavonoids, improving arithmetic, similarity testing, and short-term memory over 12 months (PMID 39317299). In healthy children aged 8-12, 100 mg/day of sunflower-derived PS showed no significant effect on primary cognitive outcomes in the total cohort, though a pre-defined subgroup of lower-performing children showed benefit on visuospatial memory (PMID 41318468). PS also plays a structural role in cell membranes and is involved in thrombotic signaling via externalization on platelet and red blood cell surfaces (PMID 41935811, PMID 41809104).

Source: auto-research

Effective Dose

100 mg/day (children, PMID 41318468); 63 mg/day as part of combination (PMID 39317299); No standalone dose established from provided studies alone