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Last verified: 10 days ago

Pomella® Pomegranate Extract

Also known as: AcuraGlow, BlueActiv, Pomella, pomegranate extract, punicalagins, Punica granatum

Evidence under review. — Not yet rated

Patented pomegranate extract with antioxidant polyphenols; early evidence for skin and gut health.

  • What it does

    Pomella® is a patented, standardized pomegranate fruit extract concentrated in punicalagins — potent antioxidant polyphenols found in pomegranate. According to web-sourced studies, daily...

  • Evidence quality

    Evidence base hasn't been formally rated yet. See research below.

  • Clinical dose

    75-250 mg daily (standardized to punicalagins)

See full breakdown ↓ Methodology →

What the Science Says

Pomella® is a patented, standardized pomegranate fruit extract concentrated in punicalagins — potent antioxidant polyphenols found in pomegranate. According to web-sourced studies, daily supplementation (250 mg standardized to 75 mg punicalagins) over four weeks may improve skin health markers and support gut microbiome diversity. Broader pomegranate extract research suggests potential benefits for inflammatory markers linked to cardiovascular health, though most evidence comes from industry-adjacent sources rather than independently verified clinical trials.

What It Doesn't Do

Not proven to cure or treat any disease. Brain and memory benefits are speculative — no peer-reviewed trials in the provided data confirm this. Don't expect dramatic results from a single short-term study. 'Patented' doesn't mean clinically superior to regular pomegranate extract.

Evidence-Based Benefits

Four weeks of daily use improved multiple skin health markers in a randomized controlled trial.

Weak Evidence

Effective at: 250 mg daily (75 mg punicalagins)

May support gut microbiome diversity when taken daily for at least four weeks.

Weak Evidence

Effective at: 250 mg daily (75 mg punicalagins)

Pomegranate extract broadly associated with reductions in hs-CRP, IL-6, and TNF-α in meta-analysis data.

Weak Evidence

Effective at: No established dose from provided data

Absorption & Bioavailability

Unknown from provided data. Punicalagins are metabolized into urolithins by gut bacteria, meaning absorption and benefit may vary significantly between individuals depending on microbiome composition.

Red Flags to Watch For

  • No PubMed-indexed papers were available for direct review — all claims rely on web sources, including manufacturer-adjacent content
  • AcuraGlow® and BlueActiv® appear to be brand aliases with no independently published clinical data found in this review
  • Most web sources promoting Pomella® are supplement retailer blogs, not peer-reviewed journals — treat health claims cautiously
  • Urolithin conversion (needed for full benefit) varies widely by individual gut microbiome — some people may get little to no effect
  • Short study duration (4 weeks) limits conclusions about long-term safety or efficacy

Frequently Asked Questions

What does Pomella® Pomegranate Extract do?

Patented pomegranate extract with antioxidant polyphenols; early evidence for skin and gut health.

What is the effective dose of Pomella® Pomegranate Extract?

75-250 mg daily (standardized to punicalagins)

Is Pomella® Pomegranate Extract safe?

No PubMed-indexed papers were available for direct review — all claims rely on web sources, including manufacturer-adjacent content

What doesn't Pomella® Pomegranate Extract do?

Not proven to cure or treat any disease.

Research Sources

  • Web

This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Last updated: 2026-10-30