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Pongamol

Also known as: Pongamia pinnata flavonoid, furanoflavone, Millettia pinnata constituent, karanja flavonoid

Effective Dosage

No established dose (insufficient research data)

What the Science Says

Pongamol is a flavonoid compound extracted from the seeds and fruits of Pongamia pinnata (also called Millettia pinnata or karanja tree), a plant used in traditional Ayurvedic medicine. Early laboratory and animal studies suggest it may have antioxidant, anti-inflammatory, blood sugar-lowering, and neuroprotective properties, with one animal study showing modest blood glucose reductions at 50–100 mg/kg doses. All research to date has been conducted in cell cultures or rodent models — no human clinical trials have been completed.

What It Doesn't Do

Not proven to treat diabetes, Alzheimer's, or cancer in humans. No human safety data exists for supplement use. Lab results in mice do not mean it works in people. Not a proven antioxidant supplement for humans. No evidence it prevents or reverses any disease.

Evidence-Based Benefits

Pongamol is a flavonoid compound extracted from the seeds and fruits of Pongamia pinnata (also called Millettia pinnata or karanja tree), a plant used in traditional Ayurvedic medicine. Early laboratory and animal studies suggest it may have antioxidant, anti-inflammatory, blood sugar-lowering, and neuroprotective properties, with one animal study showing modest blood glucose reductions at 50–100 mg/kg doses. All research to date has been conducted in cell cultures or rodent models — no human clinical trials have been completed.

Weak Evidence

Effective at: No established dose (insufficient research data)

Source: auto-research

Absorption & Bioavailability

Unknown — no human pharmacokinetic or bioavailability studies were found in the provided research

Red Flags to Watch For

  • Zero human clinical trials — all evidence comes from cell cultures and animal studies
  • No established safe dose for human consumption as a supplement
  • No registered supplement products found in NIH DSLD, meaning no regulatory oversight of products claiming to contain it
  • Toxicology data exists only for Pongamia oil, not isolated pongamol — safety of concentrated pongamol supplements is unknown
  • Mosquito larvicide activity suggests biological potency that warrants caution at high doses

Products Containing Pongamol

See how Pongamol is used in these analyzed products:

Research Sources

  • PubMed
  • NIH DSLD

This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Last updated: 2026-04-09