Does Red Raspberry Leaf Help With In vitro screening identified red raspberry leaf extract ...?

Evidence Summary

In vitro screening identified red raspberry leaf extract as a potential inhibitor of intestinal DGAT1 enzyme activity (IC50 = 5.6 μg/mL), but this did not translate to significant clinical benefit in a 7-day human trial where only grape extract reduced postprandial triglycerides (PMID: 26246845). In vitro rat uterine studies showed variable and inconsistent effects on uterine contractility depending on preparation type and pregnancy status, with no clear augmentation of labor contractions (PMID: 20220111). Maternal exposure in rats altered cytochrome P450 enzyme activity in female offspring, suggesting potential pharmacokinetic interactions (PMID: 21115944).

Source: auto-research

Effective Dose

No established dose