Does Reishi Mushroom Help With Reishi polysaccharides and beta-glucans show immunomodula...?
Weak EvidenceEvidence Summary
Reishi polysaccharides and beta-glucans show immunomodulatory and anti-inflammatory activity in animal and in vitro models, including suppression of pro-inflammatory cytokines (TNF-α, IL-6, IL-1β) and reduction of oxidative stress markers (PMID: 38967209, PMID: 38290027, PMID: 37670115). In a mouse model of atopic dermatitis, Reishi polysaccharides modulated gut microbiota, reduced IgE and IL-4 levels, and helped restore skin barrier function (PMID: 41606936). A single small crossover clinical trial in Gulf War Illness patients was conducted, but full efficacy results were not reported in the available abstract (PMID: 33915962).
Source: auto-research
Effective Dose
No established dose from provided studies