Does Rose Hip Extract Help With Rose hip extract contains polyphenolics (proanthocyanidin...?

Evidence Summary

Rose hip extract contains polyphenolics (proanthocyanidins, flavonoids) that demonstrate antioxidant activity by inhibiting reactive oxygen species in vitro (PMID: 11933119). In animal models, a hot-water rose hip extract showed anti-prediabetic effects by improving glucose tolerance (PMID: 28182280). A pilot study in humans found rose hip shell powder may inhibit cytokine expression via lipophilic fractions, suggesting anti-inflammatory potential, though no significant improvement over a comparator powder was observed in pain outcomes (PMID: 25043856).

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Effective Dose

No established dose from provided studies for standalone use; used as 50 mg in combination formula (PMID: 24051943); up to 20 g/day powder in pain study (PMID: 25043856)