Sodium Bicarbonate
Also known as: baking soda, NaHCO3, bicarb, sodium hydrogen carbonate
Effective Dosage
0.3 g/kg body weight for performance (based on study doses)
What the Science Says
Sodium bicarbonate is a simple alkaline salt — the same compound as baking soda — that raises the pH of your blood and muscles. During high-intensity exercise, your muscles produce acid that causes fatigue; sodium bicarbonate acts as a buffer, soaking up that acid and delaying the burn. Studies show it can improve anaerobic performance and muscular endurance, and combining it with glycerol may also improve fluid retention before exercise. A typical dose used in research is 0.3 g per kilogram of body weight.
What It Doesn't Do
Won't help with endurance or aerobic sports in any meaningful way. Not a fat burner or weight loss aid. No evidence it builds muscle directly. The cancer-fighting claims you see online are based on very early animal and lab research — don't count on it as a cancer treatment. Won't replace medical care for serious conditions like hyponatremia or poisoning.
Evidence-Based Benefits
Sodium bicarbonate is a simple alkaline salt — the same compound as baking soda — that raises the pH of your blood and muscles. During high-intensity exercise, your muscles produce acid that causes fatigue; sodium bicarbonate acts as a buffer, soaking up that acid and delaying the burn. Studies show it can improve anaerobic performance and muscular endurance, and combining it with glycerol may also improve fluid retention before exercise. A typical dose used in research is 0.3 g per kilogram of body weight.
Moderate EvidenceEffective at: 0.3 g/kg body weight for performance (based on study doses)
Source: auto-research
Absorption & Bioavailability
Good — rapidly absorbed orally and quickly raises blood bicarbonate levels within 60–90 minutes of ingestion
Red Flags to Watch For
- Can cause significant gastrointestinal distress (nausea, bloating, diarrhea) at performance doses of 0.3 g/kg — a well-documented side effect
- High sodium content may be a concern for people with hypertension, heart disease, or kidney problems
- Medical IV use (e.g., for hyponatremia or poisoning) is a clinical procedure — do not attempt at home
- Transdermal and anti-cancer applications are experimental and not ready for consumer use
Products Containing Sodium Bicarbonate
See how Sodium Bicarbonate is used in these analyzed products:
Research Sources
- PubMed
- NIH DSLD
This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Last updated: 2026-04-09