Does Tart Cherry Extract Help With Tart cherry extract, rich in anthocyanins, has shown anti...?

Evidence Summary

Tart cherry extract, rich in anthocyanins, has shown antioxidant and anti-inflammatory properties in limited human and animal studies. In one small RCT (n=13), 500 mg/day for 7 days reduced oxidative stress markers (protein carbonyl) and muscle damage indicators (CK, CK-MB) following intense resistance exercise, and prevented handgrip strength decline (PMID: 34126996). Animal studies suggest it may reduce inflammatory cytokines (IL-6, leptin) and improve antioxidant capacity in obesity models (PMID: 31438590), and reduce amyloid-beta deposition and behavioral deficits in Alzheimer's mouse models when combined with omega fatty acids (PMID: 34827424).

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Effective Dose

No established dose from provided studies; 500 mg/day used in one human RCT