Does Tongkat Ali Help With In men with androgen deficiency of aging (ADAM), 200 mg/d...?

Evidence Summary

In men with androgen deficiency of aging (ADAM), 200 mg/day combined with concurrent exercise training improved erectile function and total testosterone levels over 6 months, though the standalone supplement effect was not isolated (PMID: 33541567). A 4-week RCT in middle-aged Japanese adults found 200 mg/day of Physta® improved immune parameters including total T-cell counts and immunological vigor scores compared to placebo (PMID: 26816234). Animal studies suggest possible benefits for sleep consolidation and thermoregulation (PMIDs: 39055967, 36047106), and rat models showed protective effects on testicular function against chemotherapy-induced damage (PMID: 39369924).

Source: auto-research

Effective Dose

200 mg/day (standardized water extract) based on clinical trials; animal studies used 400-800 mg/kg