HypeCheck

Watercress

Also known as: Nasturtium officinale, garden cress, water cress, PEITC source

Effective Dosage

85 g/day (fresh) or 500–750 mg/day (extract) based on study doses

What the Science Says

Watercress is a peppery aquatic leafy green packed with glucosinolates — plant compounds that convert to isothiocyanates (especially PEITC) in the body. Clinical trials show it can reduce markers of oxidative stress and inflammation, lower LDL cholesterol in overweight individuals, and significantly boost the body's ability to detoxify environmental carcinogens like benzene and acrolein. A 2-week watercress drink study found up to 65% increases in detoxification of acrolein and 37% for benzene. Benefits in human trials typically appeared within 3–5 weeks of supplementation.

What It Doesn't Do

Won't meaningfully lower blood sugar — one trial showed lettuce beat watercress for glycemic control. Doesn't significantly change total cholesterol, triglycerides, or HDL on its own. No solid evidence it treats or prevents cancer in humans. Not a proven hair loss treatment. Eating it occasionally won't replicate the concentrated doses used in studies.

Evidence-Based Benefits

Watercress is a peppery aquatic leafy green packed with glucosinolates — plant compounds that convert to isothiocyanates (especially PEITC) in the body. Clinical trials show it can reduce markers of oxidative stress and inflammation, lower LDL cholesterol in overweight individuals, and significantly boost the body's ability to detoxify environmental carcinogens like benzene and acrolein. A 2-week watercress drink study found up to 65% increases in detoxification of acrolein and 37% for benzene. Benefits in human trials typically appeared within 3–5 weeks of supplementation.

Moderate Evidence

Effective at: 85 g/day (fresh) or 500–750 mg/day (extract) based on study doses

Source: auto-research

Absorption & Bioavailability

Moderate — PEITC and other isothiocyanates are released during chewing and digestion, but bioavailability varies by preparation method. Freeze-dried and extract forms used in trials may differ from raw consumption.

Red Flags to Watch For

  • Raw watercress grown in or near water can carry Fasciola hepatica (liver fluke) — a real parasitic infection risk, especially from wild-harvested sources
  • Watercress is high in vitamin K, which can interfere with blood thinners like warfarin
  • Supplement doses (mg/kg/day) used in trials are much higher than typical dietary intake — don't assume eating a salad delivers the same effect
  • Most human trials are small (15–65 participants) and short (3–5 weeks), limiting confidence in long-term safety and efficacy
  • No standardized dosing exists across products — the 865 registered supplement products likely vary widely in PEITC content

Products Containing Watercress

See how Watercress is used in these analyzed products:

Research Sources

  • PubMed
  • NIH DSLD

This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Last updated: 2026-04-09