ADAM™ Men's Multiple Vitamin Review 2026: Worth the Price?

Possible side effects

• Adverse effects are described as mild and infrequent, and may include digestive symptoms, dizziness, and headache.

Avoid or ask a doctor first if

• Saw palmetto may be unsafe during pregnancy or while breastfeeding.

Medication interactions

• The source advises talking with a health care provider before using any herbal product if you take medicine, because some herbs and medicines interact in harmful ways. No specific drug interactions are named for saw palmetto.

Possible side effects

• Insomnia or digestive upsets may occur.

Serious risks

• The source says no serious side effects have been reported.

Avoid or ask a doctor first if

• CoQ10 may not be compatible with some types of cancer treatment.

Medication interactions

• CoQ10 may interact with the blood thinner warfarin and the diabetes drug insulin.

Avoid or ask a doctor first if

• Little is known about whether grape seed extract is safe during pregnancy or breastfeeding.

Medication interactions

• People who take any medicine should talk with a health care provider before using grape seed extract, because some herbs and medicines interact in harmful ways.

Possible side effects

• Topical aloe gel is generally well tolerated, with occasional reports of burning, itching, rash, and eczema.
• Oral aloe latex can cause abdominal pain, cramps, and diarrhea.

Serious risks

• Oral aloe leaf extracts have been related to cases of acute hepatitis, with use as short as 3 weeks and as long as 5 years.
• Some animal studies found an association between oral non-decolorized aloe vera leaf extract and gastrointestinal cancer in rats and mice.
• A small amount of lab research suggests even decolorized extract might have the potential to damage DNA or chromosomes.
• The International Agency for Research on Cancer has classified whole leaf extract of aloe vera as a possible human carcinogen.
• The form classified as a possible carcinogen is called non-decolorized and has not had activated carbon treatment to remove toxic anthraquinone components.

Avoid or ask a doctor first if

• Aloe taken by mouth, in gel, latex, or whole leaf extract form, may be unsafe during pregnancy and while breastfeeding.

Medication interactions

• Overuse of aloe latex may increase the risk of adverse effects from cardiac glycosides such as digoxin.
• Some herbs and medicines interact in harmful ways.

Possible side effects

• High zinc intakes can cause nausea, dizziness, headaches, gastric distress, vomiting, and loss of appetite.

Serious risks

• Doses of 50 mg or more taken for weeks can interfere with copper absorption, reduce immune function, and lower HDL cholesterol.
• Very high supplemental doses (142 mg/day) might interfere with magnesium absorption and disrupt magnesium balance.
• According to a few reports, overuse of zinc-containing denture adhesive creams can lead to neurological symptoms and anemia.

Avoid or ask a doctor first if

• The upper limits don't apply to people receiving zinc for medical treatment, who should be under a physician's care.
• Zinc-free denture adhesive formulations are available to prevent the effects linked to zinc-containing creams.

Medication interactions

• Zinc may interact with quinolone antibiotics, tetracycline antibiotics, and penicillamine.
• Some diuretics can lower serum zinc by increasing zinc excretion in urine.
• People taking medications regularly should discuss their zinc status with their health care providers.

Possible side effects

• The most common complaints are diarrhea, nausea, abdominal cramps, and other digestive upset.

Serious risks

• High intakes may raise urinary oxalate and uric acid, which could contribute to kidney stones, especially in people with renal disorders.
• The best evidence that vitamin C contributes to kidney stones is in patients who already have hyperoxaluria.
• In people with hereditary hemochromatosis, long-term high doses could worsen iron overload and cause tissue damage.
• A few in vitro studies suggested that supplemental oral vitamin C, acting as a pro-oxidant, could cause chromosomal or DNA damage and possibly contribute to cancer.
• In postmenopausal women with diabetes in the Iowa Women's Health Study, supplemental vitamin C of at least 300 mg/day was significantly associated with a higher risk of dying from CVD.

Avoid or ask a doctor first if

• People with hereditary hemochromatosis face a concern about iron overload with chronic high doses.
• The upper limits do not apply to people receiving vitamin C as medical treatment, who should be under a physician's care.
• Infants should get vitamin C only from formula and food.

Medication interactions

• Vitamin C supplements may interact with radiation therapy and with medications, including chemotherapy drugs and statins.
• People taking these medications regularly should talk with their health care providers about vitamin C intake.

Possible side effects

• High blood calcium from vitamin D toxicity can lead to nausea, vomiting, muscle weakness, and other symptoms.

Serious risks

• Toxicity can cause high blood and urine calcium. In extreme cases it may lead to kidney failure, soft tissue calcification, heart rhythm problems, and death.
• Toxicity is almost always caused by taking too much vitamin D through supplements.

Avoid or ask a doctor first if

• The source says people on regular medications should talk with their health care providers about vitamin D intake and status.

Medication interactions

• Vitamin D supplements may interact with orlistat, statins, steroids, and thiazide diuretics.
• Taking calcium supplements with vitamin D supplements may raise the risk of certain adverse effects.

Possible side effects

• Early signs of too much selenium are a garlic odor on the breath and a metallic taste in the mouth.
• Hair loss and nail brittleness or loss are the most common clinical signs of chronically high selenium intake.
• Other signs of chronically high intake include skin rash, nausea, diarrhea, fatigue, irritability, and nervous system abnormalities.

Serious risks

• Acute selenium toxicity can cause severe gastrointestinal and neurological symptoms, respiratory distress syndrome, heart attack, kidney failure, cardiac failure, and, in rare cases, death.
• Acute toxicity has resulted from misformulated over-the-counter products containing very large amounts of selenium. In 2008, 201 people had severe adverse reactions to a liquid supplement with 200 times the labeled amount.
• Brazil nuts contain very high amounts of selenium and could cause selenium toxicity if eaten regularly.

Avoid or ask a doctor first if

• The upper limits do not apply to people taking selenium under a physician's care.
• People who take medications regularly should discuss their selenium status with their health care providers.

Medication interactions

• Selenium supplements may interact with medications, and some medications, such as cisplatin, can affect selenium levels in the body.