2-Aminoisoheptane HCl
Also known as: DMHA, Dimethylhexylamine, Octodrine, 2-amino-6-methylheptane, 2-amino-5-methylhexane, Amidrine
Effective Dosage
No established dose
What the Science Says
2-Aminoisoheptane HCl (commonly called DMHA) is a synthetic stimulant compound structurally similar to DMAA and amphetamines. It is marketed as an energy booster and focus enhancer in pre-workout and weight-loss supplements, claimed to work by stimulating the central nervous system and increasing levels of dopamine and norepinephrine. No peer-reviewed clinical trials were available to confirm its effectiveness or establish a safe dose range for humans.
What It Doesn't Do
No clinical proof it burns fat on its own. No evidence it meaningfully improves athletic performance in humans. Not a safe or proven substitute for caffeine. Not approved as a dietary ingredient by the FDA. Marketing claims about 'euphoric focus' and 'extreme energy' are not backed by published human trials.
Evidence-Based Benefits
2-Aminoisoheptane HCl (commonly called DMHA) is a synthetic stimulant compound structurally similar to DMAA and amphetamines. It is marketed as an energy booster and focus enhancer in pre-workout and weight-loss supplements, claimed to work by stimulating the central nervous system and increasing levels of dopamine and norepinephrine. No peer-reviewed clinical trials were available to confirm its effectiveness or establish a safe dose range for humans.
Weak EvidenceEffective at: No established dose
Source: auto-research
Absorption & Bioavailability
Unknown — no pharmacokinetic data from provided studies or published clinical trials
Red Flags to Watch For
- FDA has flagged DMHA as an illegal ingredient in dietary supplements and issued warning letters to manufacturers
- Structurally similar to amphetamines and DMAA, which has been linked to serious cardiovascular events including heart attack and death
- No published human safety or efficacy trials — risk profile is largely unknown
- May cause dangerous increases in blood pressure and heart rate, especially when combined with caffeine or other stimulants
- Banned by WADA and prohibited in competitive sports — athletes risk positive drug tests
- Found in over 1,000 registered supplement products despite lack of safety data, suggesting widespread unregulated use
Products Containing 2-Aminoisoheptane HCl
See how 2-Aminoisoheptane HCl is used in these analyzed products:
Research Sources
- General knowledge
This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Last updated: 2026-04-12