HypeCheck
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Last verified: 17 days ago

Keratin

Also known as: hair keratin, KRT, cytokeratin, keratin protein, hydrolyzed keratin

Evidence under review. — Not yet rated

Structural protein found in hair, skin, and nails. Limited clinical evidence for supplement use.

What the Science Says

Keratin is a fibrous structural protein that makes up hair, nails, and the outer layer of skin. In the provided research, keratin appears primarily as a biological marker or measurement tool — for example, keratin-18 levels are used to assess liver disease severity, and keratin gene expression is tracked in skin conditions like psoriasis and alopecia. No clinical trials in the provided data tested oral or topical keratin supplements for hair, nail, or skin improvement in healthy adults.

What It Doesn't Do

No evidence from these studies that taking keratin supplements grows thicker hair or stronger nails. Not shown to reverse hair loss on its own. No proof it improves skin elasticity or hydration as a supplement. The research here uses keratin as a disease biomarker, not a treatment.

Evidence-Based Benefits

Hair keratin gene expression increases with effective alopecia areata treatment and correlates with hair regrowth.

Weak Evidence

Effective at: No established dose

Supporting studies (click to view on PubMed):

Keratin-18 levels are used as a clinical marker to assess liver disease activity in NAFLD patients.

Weak Evidence

Effective at: No established dose

Supporting studies (click to view on PubMed):

Absorption & Bioavailability

Unknown — no absorption or bioavailability data provided in the supplied studies

Red Flags to Watch For

  • None of the provided studies tested keratin as an oral supplement for hair, skin, or nail benefits
  • Keratin in these papers is primarily a biological marker for disease, not a therapeutic ingredient
  • 314 registered supplement products exist despite very limited clinical trial evidence for supplemental use
  • Marketing claims about hair and nail growth are not supported by any of the provided research papers

Products Containing Keratin

See how Keratin is used in these analyzed products:

Frequently Asked Questions

What does Keratin do?

Structural protein found in hair, skin, and nails. Limited clinical evidence for supplement use.

What is the effective dose of Keratin?

No established dose

Is Keratin safe?

None of the provided studies tested keratin as an oral supplement for hair, skin, or nail benefits

What doesn't Keratin do?

No evidence from these studies that taking keratin supplements grows thicker hair or stronger nails.

Research Sources

  • PubMed
  • NIH DSLD

This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Last updated: 2026-05-25