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Last verified: 17 days ago

Lychee Extract

Also known as: Litchi chinensis extract, lychee fruit extract, litchi extract, oligonol

Evidence under review. — Not yet rated

Tropical fruit extract with antioxidant properties. Human clinical evidence is very limited.

  • What it does

    Lychee extract comes from the fruit of the Litchi chinensis tree, native to Southeast Asia. It contains polyphenols and flavonoids that show antioxidant activity in lab settings. One lab study...

  • Evidence quality

    Evidence base hasn't been formally rated yet. See research below.

  • Clinical dose

    No established dose

What the Science Says

Lychee extract comes from the fruit of the Litchi chinensis tree, native to Southeast Asia. It contains polyphenols and flavonoids that show antioxidant activity in lab settings. One lab study found lychee extract inhibited an enzyme linked to blood sugar regulation, and one animal study used it as part of a multi-ingredient blend that reduced obesity markers in mice — but neither finding has been confirmed in human clinical trials.

What It Doesn't Do

Not proven to cause weight loss in humans. No clinical evidence it controls blood sugar in people. The animal study used a combo product — you can't credit lychee alone. Don't confuse lab results with real-world benefits.

Evidence-Based Benefits

Contains polyphenols that show antioxidant activity in laboratory tests.

Weak Evidence

Effective at: No established dose

Inhibits alpha-glycosidase enzyme activity in lab tests, which is linked to blood sugar control.

Weak Evidence

Effective at: No established dose

Absorption & Bioavailability

Unknown — no human pharmacokinetic data available from provided studies

Red Flags to Watch For

  • Nearly all available evidence is from lab (in vitro) or animal studies — not human trials
  • Most commercial products use lychee as part of a proprietary blend, making it impossible to isolate its effects
  • 1,000+ supplement products on the market despite only 1 indexed clinical paper — marketing far outpaces the science
  • Doses used in animal studies cannot be directly translated to human supplement doses

Products Containing Lychee Extract

See how Lychee Extract is used in these analyzed products:

Frequently Asked Questions

What does Lychee Extract do?

Tropical fruit extract with antioxidant properties. Human clinical evidence is very limited.

What is the effective dose of Lychee Extract?

No established dose

Is Lychee Extract safe?

Nearly all available evidence is from lab (in vitro) or animal studies — not human trials

What doesn't Lychee Extract do?

Not proven to cause weight loss in humans.

Research Sources

  • PMID 28643888
  • PMID 26788291
  • General knowledge — limited published research available

This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Last updated: 2026-05-25