Does Pygeum Help With Pygeum africanum bark extract has demonstrated clinically...?

Evidence Summary

Pygeum africanum bark extract has demonstrated clinically meaningful improvements in lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH), including reductions in IPSS scores (~35-46%), improved urinary flow rates, and reduced nocturia in multiple clinical trials (PMID: 10475357, PMID: 9787978). In vitro research using human serum collected after Pygeum intake showed inhibition of prostatic stromal myofibroblast proliferation and upregulation of tumor suppression pathways with downregulation of inflammation and oxidative stress genes (PMID: 22198631). Combination products containing Pygeum have also shown significant reductions in residual bladder volume and improvements in quality of life in BPH patients (PMID: 26492588).

Source: auto-research

Effective Dose

100 mg/day (once daily) or 50 mg twice daily based on clinical studies