Avmacol® Extra Strength Review 2026: Worth the Price?
Checks out. — Mostly Legit
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"Avmacol used in more sulforaphane human clinical trials than competitors"
Avmacol's broccoli extract has genuinely appeared as the study material in multiple published sulforaphane trials.
PubMed: sulforaphane clinical trials using Avmacol formulation -
"Includes active myrosinase enzyme, unlike many broccoli extract rivals"
Myrosinase is required to convert inert glucoraphanin into active sulforaphane, so this is a real formulation edge.
PubMed: sulforaphane bioavailability and myrosinase research -
"Sulforaphane + maitake supports detox better than sulforaphane alone"
Evidence shown is the company's own cell-culture images, not a published human trial comparing the two.
Internal: review of cited evidence on product page -
"No dose amounts given for glucoraphanin, myrosinase, or maitake on this page"
Without mg or activity units, you can't check if doses match amounts used in research studies.
Consumer advice
If you're interested in sulforaphane supplements, this is one of the more legitimate options on the market since it's actually been used as the study material in real human trials and includes the enzyme needed for conversion. But before buying, look up the Supplement Facts panel (not shown on this marketing page) for the actual glucoraphanin mg amount and myrosinase activity units, and don't over-interpret the "detox" and "immune support" language as disease prevention — it isn't. If cost matters, compare per-serving price against other broccoli sprout extracts with disclosed doses.
Claims vs Evidence
MODEST0 of 4 claims supported by evidence. These grades score the marketing, not the product — a claim only counts as supported when the label discloses a dose that matches the studies behind it, so blends that hide doses cap at “partial” no matter how good the formula is.
"supports your body's natural detoxification process"
Partial
Sulforaphane raises Phase 2 detox enzymes in cells; whole-body 'detox' benefit unproven.
Based on: Broccoli seed and sprout extract (glucoraphanin), Myrosinase enzyme, Maitake mushroom extract
Source: PubMed: sulforaphane NRF2/Phase 2 enzyme research
"works better than sulforaphane alone"
Stretch
Based on cell-culture images from the company, not human outcome trials.
Based on: Maitake mushroom extract
Source: Internal: company-provided cell assay data
"supports internal defense systems / immune support"
Partial
Beta-glucans show modest immune activity in some studies, not disease prevention.
Based on: Maitake mushroom extract, beta-glucans
Source: PubMed: beta-glucan immune modulation reviews
"selected for use in more sulforaphane human clinical trials than any other supplement"
Partial
Plausible and traceable to real trials, but this measures use in research, not proven health outcomes.
Based on: Sulforaphane Production System
Source: Internal: claim framing check
3 partial · 1 stretch
Ingredients
Based on peer-reviewed research from PubMed and Examine.com
Why the chain breaks for this product
Most ingredients below have real research behind them. The problem isn't the ingredients — it's the doses. 7 of 7 are not disclosed on the label, so the product can claim the benefits without delivering the chain that gets you there.
Broccoli seed and sprout extract (glucoraphanin)
Broccoli compound with antioxidant and anti-inflammatory potential. Early research is promising but limited.
Research-backed dose: Human studies commonly use ~10-40mg sulforaphane-equivalent or glucoraphanin providing that yield
In this product: Dose not disclosed
Myrosinase enzyme (Myrosimax®)
Enzyme that activates broccoli compounds. Limited clinical evidence for its benefits as a standalone supplement.
Maitake mushroom extract
Broad category of fungi extracts with early evidence for gut, immune, and hormonal support — but results are mixed.
Research-backed dose: Immune studies on maitake beta-glucan typically use 1-3g extract/day
In this product: Dose not disclosed
Common food additive used as a placebo in clinical trials. Not a therapeutic supplement.
Myrosinase enzyme
Enzyme that activates broccoli compounds. Limited clinical evidence for its benefits as a standalone supplement.
Natural fiber compound from yeast, mushrooms, or oats. Shown to support immune function and reduce respiratory infections.
Sulforaphane Production System
Broccoli compound with antioxidant and anti-inflammatory potential. Early research is promising but limited.
Price & Value
ModerateAvmacol® Extra Strength
$34.99 (30 count) / $65.99 (75 count)
Generic broccoli sprout extract or sulforaphane glucosinolate capsules (e.g., Thorne Crucera-SGS, Jarrow Broccomax)
$20-30 for 30-60 servings
Research sources: PubMed · Examine.com
Analyzed product: https://avmacol.com/products/avmacol-extra-strength
Analysis generated: 2026-09-15 · Engine v1.0.0
Frequently Asked Questions
Is Avmacol® Extra Strength worth the money?
Avmacol® Extra Strength at $34.99 (30 count) / $65.99 (75 count) appears to offer reasonable value based on its ingredient quality and dosing. Avmacol Extra Strength is a real, technically thoughtful supplement: it pairs glucoraphanin (a broccoli-derived precursor) with active myrosinase enzyme, which is genuinely necessary to convert that precursor into active sulforaphane — an advantage many rival broccoli extracts lack. But the page's boldest claim, that adding maitake mushroom works "better
Is Avmacol® Extra Strength a scam?
Avmacol® Extra Strength does not appear to be a scam. Our analysis found the claims are generally supported by the ingredients.
What are the ingredients in Avmacol® Extra Strength?
Avmacol® Extra Strength contains 7 ingredients including Broccoli seed and sprout extract (glucoraphanin), Myrosinase enzyme (Myrosimax®), Maitake mushroom extract, Maltodextrin, Myrosinase enzyme.
Does Avmacol® Extra Strength actually work?
Yes, Avmacol® Extra Strength can work for its intended purpose. 0 of 4 claims are fully supported. 3 are partially supported.
Are there cheaper alternatives to Avmacol® Extra Strength?
Yes, Generic broccoli sprout extract or sulforaphane glucosinolate capsules (e.g., Thorne Crucera-SGS, Jarrow Broccomax) at $20-30 for 30-60 servings offers similar benefits at a better price point. Many key ingredients in Avmacol® Extra Strength are available separately for less.