NOW Detox Cleanse 90ct Review 2026: Legit or Overhyped?
Read before you buy. — Overhyped
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"Milk thistle provides liver support"
Silymarin (milk thistle's active compound) has real clinical evidence for liver enzyme support — but only at 140-800mg standardized silymarin daily.
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"Detox & Cleanse your body"
The liver and kidneys filter toxins 24/7 without supplement help. No pill accelerates this process.
Examine.com: Detox supplement overview -
"Multi-herb formula for comprehensive cleansing"
7 herbs in one formula means each ingredient likely gets a fraction of its clinically studied dose. Combination blends hide underdosing.
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"Red Clover included for detox support"
Red Clover's clinical evidence is for menopause symptoms and cholesterol — not detoxification. It contains phytoestrogens.
PubMed: Ghazanfarpour et al. 2016, red clover isoflavone meta-analysis
Consumer advice
If you're interested in liver support specifically, a standalone milk thistle supplement standardized to 70-80% silymarin (140-800mg/day) is better value and has stronger evidence than a multi-herb "detox" blend. NOW Foods makes a good standalone milk thistle for ~$12-15. Skip the "detox/cleanse" framing entirely — it's marketing language, not science. If you have actual liver concerns (elevated enzymes, fatty liver), talk to a doctor rather than self-treating with supplements. This product is fine for what it is — a reputable brand, reasonable price — but don't expect it to "cleanse" anything your liver isn't already handling.
Claims vs Evidence
MODERATE4 claims assessed. These grades assess the marketing claims, not the whole product. See each explanation for the evidence and its limits.
"Detox & Cleanse"
Stretch
Liver/kidneys detox naturally; herbs support, don't 'cleanse'
Based on: Milk Thistle, Dandelion Root, Burdock Root, Artichoke
"Liver support"
Partial
Silymarin has real liver enzyme evidence at adequate doses
Based on: Milk Thistle, Artichoke Extract
"Digestive support"
Partial
Traditional use; human evidence is limited and inconsistent
Based on: Dandelion Root, Artichoke, Burdock Root
"Antioxidant support"
Partial
Antioxidant activity confirmed in lab; clinical impact unclear
Based on: Milk Thistle, Artichoke Extract, Burdock Root
3 partial · 1 stretch
Ingredients
Based on peer-reviewed research from PubMed and Examine.com
Why the chain breaks for this product
Most ingredients below have real research behind them. The problem isn't the ingredients — it's the doses. 8 of 13 are not disclosed on the label, so the product can claim the benefits without delivering the chain that gets you there.
Traditional herb with anti-inflammatory and anti-cancer activity in lab studies. No human trials yet.
In this product: 200 mg
Traditional herb used for digestion and iron absorption. Very limited clinical evidence supports its use.
In this product: 50 mg
Yellow Dock Root Extract (Rumex crispus)
Traditional herb used for digestion and iron absorption. Very limited clinical evidence supports its use.
Red Clover Extract (Trifolium pratense)
Plant-based source of isoflavones; traditionally used for menopause symptoms, but clinical evidence is limited.
Research-backed dose: 40-160 mg isoflavones daily (traditional/general use range; no confirmed clinical dose from provided studies)
In this product: Dose not disclosed
Cleavers Herb Extract (Galium aparine)
Traditional herb with no clinical trial evidence supporting any health benefit in humans.
Parsley (Petroselinum crispum) (Seed)
Common culinary herb with antioxidant properties. Human evidence is very limited and mixed.
In this product: 50 mg
Slippery Elm (Ulmus rubra) (Bark)
Tree bark used for gut soothing. Limited solo evidence; most studies test it in herbal blends.
In this product: 20 mg
Sodium Copper Chlorophyllin (Chlorophyll)
Essential trace mineral. Research covers medical uses like IUDs and Wilson disease—not general supplementation.
In this product: 10 mg
Herbal extract with antioxidant properties. Clinical evidence supports modest liver enzyme improvement and organ protection.
Research-backed dose: 70-200 mg silymarin daily based on study doses
In this product: Dose not disclosed
Traditional herb with anti-inflammatory and anti-cancer activity in lab studies. No human trials yet.
Traditional root with early evidence for reducing inflammation and supporting joint health.
Artichoke extract may support liver health and cholesterol levels, with moderate clinical evidence.
Plant extract with decent evidence for cholesterol support; does not cure hangovers or replace statins.
Safety & side effects
What NIH says about the ingredients in this product. This describes the ingredients, not tests of this product, and it is not medical advice. Ask a doctor or pharmacist first if you take medication, are pregnant or nursing, or have a health condition.
Dandelion
NCCIH says dandelion in the amounts commonly found in food is considered likely safe. Less is known about larger amounts. Allergic reactions and possible drug interactions are the main concerns it names.
Possible side effects
- Topical dandelion may cause an allergic reaction in people with atopic dermatitis (eczema), according to some evidence.
- Evidence is conflicting on whether dandelion causes an allergic reaction in people sensitive to related plants.
Avoid or ask a doctor first if
- Little is known about safety during pregnancy or breastfeeding when dandelion is used in amounts greater than those in foods.
- Topical dandelion may cause an allergic reaction in people with atopic dermatitis (eczema).
Medication interactions
- Dandelion might interact with antidiabetes, anticoagulant, antiplatelet, and water pill drugs, among others. The source says this is based on theoretical reasons.
- People who take any medicine or supplements are told to talk with their health care provider before using dandelion.
Copper
The source says chronic exposure to high levels of copper can cause liver damage and gastrointestinal symptoms. Copper toxicity is rare in healthy people without a hereditary copper homeostasis defect. The adult UL is 10,000 mcg a day from food and supplements.
Possible side effects
- High copper exposure over time can cause gastrointestinal symptoms.
Serious risks
- Chronic exposure to high levels of copper can result in liver damage.
- Copper toxicity has been reported in people who drink water with high copper levels, for example from stagnant water in copper-containing pipes and fixtures.
- People with Wilson's disease can develop neurologic and liver damage that can result in cirrhosis.
Avoid or ask a doctor first if
- People with Wilson's disease have a high risk of copper toxicity.
Medication interactions
- Copper is not known to have any clinically relevant interactions with medications.
Upper limit: 10000 mcg a day for adults 19+. This label lists 10 mg.
Source: NIH Office of Dietary Supplements, Copper: Fact Sheet for Health Professionals
Milk Thistle
NCCIH says milk thistle taken by mouth appears to be well tolerated, and the most common side effects are digestive. It also points to product quality problems, possible allergic reactions, and drug interactions, and says little is known about use in pregnancy or breastfeeding.
Possible side effects
- Milk thistle taken orally appears to be well tolerated. The most common side effects are digestive symptoms.
Serious risks
- Milk thistle may cause allergic reactions, especially in people allergic to related plants.
- Some supplements have silymarin amounts far from the label, or contain pesticides, microorganisms, or mycotoxins.
Avoid or ask a doctor first if
- People allergic to related plants such as ragweed, chrysanthemum, marigold, and daisy are named as more likely to react.
- Little is known about whether milk thistle is safe during pregnancy or breastfeeding.
Medication interactions
- People taking any medicine should talk with a health care provider before using milk thistle, since some herbs and medicines interact in harmful ways.
Price & Value
FairNOW Detox Cleanse 90ct
not specified
NOW Foods Milk Thistle 300mg (standalone)
~$12-15 for 100 capsules at most retailers
Research sources: PubMed · Examine.com
Analyzed product: https://sbnf.net/products/now-detox-cleanse-90ct
Analysis generated: 2026-06-03 · Engine v1.0.0
Frequently Asked Questions
Is NOW Detox Cleanse 90ct worth the money?
NOW Detox Cleanse 90ct at not specified is questionable value. While some ingredients have merit, the formulation is overhyped. NOW Detox & Cleanse is a multi-herb supplement from a reputable brand (NOW Foods) sold at a natural foods retailer. The core problem is the "detox and cleanse" framing — your liver and kidneys already do this, and no pill meaningfully accelerates the process. That said, some individual ingredients (like milk thistle/silymarin) have real evidence for liver enzyme support
Is NOW Detox Cleanse 90ct a scam?
NOW Detox Cleanse 90ct is not necessarily a scam, but it is overhyped. The marketing claims exceed what the ingredients can deliver.
What are the ingredients in NOW Detox Cleanse 90ct?
NOW Detox Cleanse 90ct contains 13 ingredients including Dandelion Root Extract (Taraxacum officinale), Burdock Root Extract (Arctium lappa), Yellow Dock Root Extract (Rumex crispus), Red Clover Extract (Trifolium pratense), Cleavers Herb Extract (Galium aparine).
Does NOW Detox Cleanse 90ct actually work?
NOW Detox Cleanse 90ct may provide some benefits, but results vary. 0 of 4 claims are fully supported. 3 are partially supported.
Are there cheaper alternatives to NOW Detox Cleanse 90ct?
Yes, NOW Foods Milk Thistle 300mg (standalone) at ~$12-15 for 100 capsules at most retailers offers similar benefits at a better price point. Many key ingredients in NOW Detox Cleanse 90ct are available separately for less.
Does NOW Detox Cleanse 90ct have side effects?
NIH summaries of the ingredients in NOW Detox Cleanse 90ct note these possible effects. Dandelion: Topical dandelion may cause an allergic reaction in people with atopic dermatitis (eczema), according to some evidence. Copper: High copper exposure over time can cause gastrointestinal symptoms. Milk Thistle: Milk thistle taken orally appears to be well tolerated. The most common side effects are digestive symptoms. This describes the ingredients, not tests of this product; ask a doctor or pharmac