HypeCheck
Last verified: 20 days ago

NOW Detox Cleanse 90ct Review 2026: Legit or Overhyped?

Read before you buy. — Overhyped

  • "Milk thistle provides liver support"

    Silymarin (milk thistle's active compound) has real clinical evidence for liver enzyme support — but only at 140-800mg standardized silymarin daily.

  • "Detox & Cleanse your body"

    The liver and kidneys filter toxins 24/7 without supplement help. No pill accelerates this process.

    Examine.com: Detox supplement overview
  • "Multi-herb formula for comprehensive cleansing"

    7 herbs in one formula means each ingredient likely gets a fraction of its clinically studied dose. Combination blends hide underdosing.

  • "Red Clover included for detox support"

    Red Clover's clinical evidence is for menopause symptoms and cholesterol — not detoxification. It contains phytoestrogens.

    PubMed: Ghazanfarpour et al. 2016, red clover isoflavone meta-analysis

Consumer advice

If you're interested in liver support specifically, a standalone milk thistle supplement standardized to 70-80% silymarin (140-800mg/day) is better value and has stronger evidence than a multi-herb "detox" blend. NOW Foods makes a good standalone milk thistle for ~$12-15. Skip the "detox/cleanse" framing entirely — it's marketing language, not science. If you have actual liver concerns (elevated enzymes, fatty liver), talk to a doctor rather than self-treating with supplements. This product is fine for what it is — a reputable brand, reasonable price — but don't expect it to "cleanse" anything your liver isn't already handling.

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Claims vs Evidence

MODERATE

0 of 4 claims supported by evidence.

"Detox & Cleanse" Stretch

Liver/kidneys detox naturally; herbs support, don't 'cleanse'

Based on: Milk Thistle, Dandelion Root, Burdock Root, Artichoke

"Liver support" Partial

Silymarin has real liver enzyme evidence at adequate doses

Based on: Milk Thistle, Artichoke Extract

"Digestive support" Partial

Traditional use; human evidence is limited and inconsistent

Based on: Dandelion Root, Artichoke, Burdock Root

"Antioxidant support" Partial

Antioxidant activity confirmed in lab; clinical impact unclear

Based on: Milk Thistle, Artichoke Extract, Burdock Root

3 partial · 1 stretch

Ingredients

Evidence: strong · moderate · weak · debunked

Based on peer-reviewed research from PubMed and Examine.com

This product does not disclose individual ingredient doses.

Traditional herb with promising lab results for gut health and anti-cancer activity, but zero human clinical trials.

weak

Research-backed dose: No established dose from provided studies

Traditional root herb with early evidence for reducing inflammation and supporting blood lipids.

moderate

Research-backed dose: No established dose from provided studies

Yellow Dock Root Extract (Rumex crispus)

Traditional herb with very limited safety data and a documented risk of serious blood platelet side effects.

weak

Research-backed dose: No established dose

Red Clover Extract (Trifolium pratense)

Plant estrogen source. Best evidence for easing menopause symptoms and improving cholesterol in postmenopausal women.

moderate

Research-backed dose: 40-160 mg/day isoflavones based on study doses

Cleavers Herb Extract (Galium aparine)

Traditional herb with zero clinical trial evidence. No proven human health benefits from available research.

weak

Research-backed dose: No established dose

Herbal extract with antioxidant properties. Clinical evidence supports modest liver enzyme improvement and organ protection.

moderate

Research-backed dose: 70-200 mg silymarin daily based on study doses

Traditional herb with promising lab results for gut health and anti-cancer activity, but zero human clinical trials.

weak

Research-backed dose: No established dose from provided studies

Traditional root herb with early evidence for reducing inflammation and supporting blood lipids.

moderate

Research-backed dose: No established dose from provided studies

Plant extract with moderate evidence for liver health and cholesterol support, especially as part of a blend.

moderate

Research-backed dose: No established dose from provided studies alone

Plant extract with decent evidence for cholesterol support; does NOT cure hangovers or replace statins.

moderate

Research-backed dose: No established dose from provided studies alone; combination products used in trials

Price & Value

Fair

NOW Detox Cleanse 90ct

Not explicitly shown in extracted content

NOW Foods Milk Thistle 300mg (standalone)

~$12-15 for 100 capsules at most retailers

Subscription: None detected

Research sources: PubMed · Examine.com

Analyzed product: https://sbnf.net/products/now-detox-cleanse-90ct

Analysis generated: 2026-05-02 · Engine v1.0.0