Does Quercetin Help With Quercetin has shown symptomatic improvement in an open-la...?

Evidence Summary

Quercetin has shown symptomatic improvement in an open-label trial for interstitial cystitis, with significant reductions in pain and symptom indices after 4 weeks at 500 mg twice daily, though this lacked a placebo control (PMID: 11272677). It has demonstrated anti-inflammatory effects via NLRP3 inflammasome inhibition in animal models of pre-eclampsia when combined with aspirin (PMID: 36136273). In vitro, quercetin protected endothelial progenitor cells from high-glucose-induced damage through Sirt1-dependent eNOS upregulation, suggesting potential vascular benefits in diabetic contexts (PMID: 25197782).

Source: auto-research

Effective Dose

500-1000 mg/day based on clinical study doses (No established optimal dose from provided studies)