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Possible side effects

• Possible side effects include drowsiness, dizziness, and confusion.

Serious risks

• Taken with anesthesia or other medicines used before and after surgery, passionflower might slow down the nervous system too much.
• Use in pregnancy may induce uterine contractions and possibly lead to other problems.

Avoid or ask a doctor first if

• Pregnant people should not use passionflower.
• People taking passionflower within 2 weeks of a scheduled surgery should talk to their health care provider.
• Little is known about whether passionflower is safe while breastfeeding.

Medication interactions

• Passionflower might interact with some anesthesia drugs.
• People who take any medicine should talk with their provider before using passionflower, since some herbs and medicines interact in harmful ways.

Possible side effects

• Side effects reported in short-term adult studies included headache, dizziness, nausea, and sleepiness.
• In children, reported side effects have included drowsiness, more bedwetting or evening urination, headache, dizziness, and agitation.
• Melatonin may stay active longer in older people and cause daytime drowsiness.

Serious risks

• Over-the-counter melatonin might put children and teenagers at risk for accidental or intentional overdose.
• In poison control data on people 19 and younger, five people needed mechanical ventilation and two children under 2 died. The data did not show whether melatonin overdose or another cause led to the deaths.
• Melatonin supplements could affect hormonal development in children, including puberty, menstrual cycles, and prolactin overproduction. The source says this isn't known for sure.
• There may be a risk of allergic reactions to melatonin supplements.
• Some melatonin products may not contain what the label says. In one study, 26 percent of supplements contained serotonin.

Avoid or ask a doctor first if

• The 2015 American Academy of Sleep Medicine guidelines recommend against melatonin use by people with dementia.
• Parents should speak with a health care provider before giving children melatonin.
• Research on melatonin safety in pregnant or breastfeeding women has been lacking.

Medication interactions

• People who take medicine should consult their health care providers before using melatonin.
• People with epilepsy and those taking blood thinner medications need medical supervision when taking melatonin supplements.

Possible side effects

• Taken by mouth, ginger can cause abdominal discomfort, heartburn, diarrhea, and mouth and throat irritation.

Avoid or ask a doctor first if

• If you're considering ginger while pregnant, consult your health care provider, as with all herbal supplements.
• Little is known about whether ginger is safe while breastfeeding.

Medication interactions

• If you take any medicine, talk with your health care provider before using ginger or other herbal products, because some herbs and medicines interact in harmful ways.

Possible side effects

• Larger amounts or long-term use are sometimes linked to gastrointestinal problems or allergic reactions.
• Topical cinnamon oil or powder may cause skin irritation or contact dermatitis, according to reports.

Serious risks

• Interactions between coumarin, a chemical in cassia cinnamon, and the liver have been reported.
• Swallowing cinnamon powder in the "cinnamon challenge" is called unsafe, and serious harm is possible.

Avoid or ask a doctor first if

• Ceylon cinnamon in larger amounts during pregnancy is considered unsafe.
• Prolonged use of cassia cinnamon could be an issue for sensitive people, such as those with liver disease.

Medication interactions

• Some components of cinnamon may interact with an anticancer medicine or nicotine, for theoretical reasons.