Last verified: 17 days ago
Spirulina
Also known as: Arthrospira platensis, Spirulina platensis, blue-green algae, Spiralin
Evidence under review. — Not yet rated
Nutrient-dense microalgae with anti-inflammatory and antioxidant effects supported by clinical trials.
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What it does
Spirulina is a blue-green microalgae packed with protein, phycocyanin, and antioxidants. Clinical trials show it can reduce pro-inflammatory markers like IL-1β and IL-6, and may improve physical...
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Evidence quality
Evidence base hasn't been formally rated yet. See research below.
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Clinical dose
1-6 g daily based on clinical studies
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Found in
AG1 (Athletic Greens), 1st Phorm Opti-Greens 50, Maximum Vibrance and 17 more
What the Science Says
Spirulina is a blue-green microalgae packed with protein, phycocyanin, and antioxidants. Clinical trials show it can reduce pro-inflammatory markers like IL-1β and IL-6, and may improve physical quality of life in people with inflammatory conditions. At doses of 1–6 g per day over 12 weeks, it has shown modest benefits for inflammation, lipid profiles, and body weight in specific populations.
What It Doesn't Do
Not a cure for any disease. Won't replace medications for MS, obesity, or heart disease. No strong evidence it boosts athletic performance on its own. Topical spirulina extracts for skin are very early-stage — don't expect dramatic eczema results. Animal and lab studies don't automatically translate to humans.
Evidence-Based Benefits
Reduces pro-inflammatory markers IL-1β and IL-6 in people with inflammatory conditions.
Moderate EvidenceEffective at: 1-6 g daily for 12 weeks
Supporting studies (click to view on PubMed):
Improves physical function, energy, and health perception in multiple sclerosis patients.
Moderate EvidenceEffective at: 1 g daily for 12 weeks
Supporting studies (click to view on PubMed):
Combined with exercise, improves anti-inflammatory and lipid-related blood markers in obese men.
Moderate EvidenceEffective at: 6 g daily for 12 weeks
Supporting studies (click to view on PubMed):
Topical spirulina extract may improve skin bacterial diversity in atopic dermatitis lesions.
Weak EvidenceEffective at: Topical gel (concentration not specified) for 4 weeks
Supporting studies (click to view on PubMed):
Absorption & Bioavailability
Moderate — phycocyanin and other bioactives are absorbed, but fresh biomass degrades quickly; dried/capsule forms are more stable. No direct human bioavailability data in the provided studies.
Red Flags to Watch For
- Fresh spirulina is highly perishable — shelf life is only 8–36 days depending on storage temperature; improper storage can lead to microbial contamination
- Most dramatic results in the provided studies come from combining spirulina with exercise (HIIT), not spirulina alone — solo supplementation effects are more modest
- Many supporting studies are in animals (dogs, chickens, rats, fish) — human evidence is limited and often in specific disease populations
- Spirulina can be contaminated with heavy metals or microcystins if sourced from unregulated suppliers — always choose third-party tested products
- The MS trial used only 1 g/day with 20% dropout rate — long-term safety and efficacy in chronic disease management is not established
Products Containing Spirulina
See how Spirulina is used in these analyzed products:
AG1 (Athletic Greens)
Supplement
1st Phorm Opti-Greens 50
Maximum Vibrance
Supplement
310 Nutrition Vanilla Crème Shake
Supplement
Zena Nutrition Organic Super Greens Powder
Supplement
Wild Society Clear Whey Isolate with Electrolytes
Supplement
Texas SuperFood Original Capsules
Supplement
Sun Chlorella Tablets 200 Mg
Supplement
WonderGreens Veggie Gummies
Supplement
310 Chocolate Icing Shake
Supplement
HealthForce SuperFoods Vitamineral Green
Supplement
Amazing Grass Organic Supergreens Powder
Supplement
Blue Majik
Supplement
Bloom Nutrition Superfood Greens Powder
Supplement
Greens by Inspired Nutraceuticals
Supplement
Transformation Super Greens (SPR BODY)
Supplement
Country Farms Collagen + Greens Powder
Supplement
Amazing Grass Super Greens The Original
Supplement
Green Vibrance
Supplement
Huel Daily Greens
Supplement
Frequently Asked Questions
What does Spirulina do?
Nutrient-dense microalgae with anti-inflammatory and antioxidant effects supported by clinical trials.
What is the effective dose of Spirulina?
1-6 g daily based on clinical studies
Is Spirulina safe?
Fresh spirulina is highly perishable — shelf life is only 8–36 days depending on storage temperature; improper storage can lead to microbial contamination
What doesn't Spirulina do?
Not a cure for any disease.
Research Sources
- PubMed
- NIH DSLD
This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement regimen. Last updated: 2026-05-25