Natrol Sleep & Restore Gummies Review 2026: Worth the Price?

Possible side effects

• Side effects reported in short-term adult studies included headache, dizziness, nausea, and sleepiness.
• In children, reported side effects have included drowsiness, more bedwetting or evening urination, headache, dizziness, and agitation.
• Melatonin may stay active longer in older people and cause daytime drowsiness.

Serious risks

• Over-the-counter melatonin might put children and teenagers at risk for accidental or intentional overdose.
• In poison control data on people 19 and younger, five people needed mechanical ventilation and two children under 2 died. The data did not show whether melatonin overdose or another cause led to the deaths.
• Melatonin supplements could affect hormonal development in children, including puberty, menstrual cycles, and prolactin overproduction. The source says this isn't known for sure.
• There may be a risk of allergic reactions to melatonin supplements.
• Some melatonin products may not contain what the label says. In one study, 26 percent of supplements contained serotonin.

Avoid or ask a doctor first if

• The 2015 American Academy of Sleep Medicine guidelines recommend against melatonin use by people with dementia.
• Parents should speak with a health care provider before giving children melatonin.
• Research on melatonin safety in pregnant or breastfeeding women has been lacking.

Medication interactions

• People who take medicine should consult their health care providers before using melatonin.
• People with epilepsy and those taking blood thinner medications need medical supervision when taking melatonin supplements.

Possible side effects

• High doses from supplements or medications can cause diarrhea, nausea, and abdominal cramping.
• Magnesium carbonate, chloride, gluconate, and oxide are the forms most commonly reported to cause diarrhea.

Serious risks

• Very high doses can lead to magnesium toxicity, with low blood pressure, vomiting, difficulty breathing, irregular heartbeat, cardiac arrest and other signs.
• A few cases of fatal hypermagnesemia have been reported.
• Very large doses of magnesium-containing laxatives and antacids have been associated with magnesium toxicity.
• The risk of toxicity increases with impaired kidney function or kidney failure.

Avoid or ask a doctor first if

• People with impaired kidney function or kidney failure face higher risk of magnesium toxicity.
• People taking medications regularly should discuss their magnesium intake with their health care providers.

Medication interactions

• Magnesium may interact with oral bisphosphonates, tetracyclines, and quinolone antibiotics.
• Some medications, including diuretics and proton pump inhibitors, can affect magnesium status.

Possible side effects

• Side effects are uncommon and may include nausea, dizziness, and allergic reactions in some people.
• Chamomile used near the eyes might cause eye irritation.

Serious risks

• Allergic reactions can include severe hypersensitivity reactions and anaphylaxis.
• Chamomile might worsen conditions sensitive to estrogen, such as breast or uterine cancer.

Avoid or ask a doctor first if

• People allergic to related plants are more likely to react to chamomile.
• Little is known about safety during pregnancy or breastfeeding.
• Chamomile might have some of the same effects as estrogen.

Medication interactions

• Taking chamomile with birth control pills might decrease the pills' effects, according to preliminary studies.
• Interactions have been reported with warfarin and some drugs metabolized by the liver; sedatives are a theoretical concern.
• People taking any medicine should talk with a health care provider before using chamomile.